European Commission

Proposed revised Annex 11 and new Annex 22 on Artificial Intelligence

Horizon-scanning material for computerized systems and AI in applicable GMP manufacturing contexts.

Authority
European Commission
Source
Proposed revised Annex 11 and new Annex 22 on Artificial Intelligence
Type
Consultation drafts
Status
Consultation closed; not effective
Publication date
7 July 2025
Effective date
Not effective
Last reviewed
12 September 2026
Topics
CSV / CSA · AI · Data Integrity · Cybersecurity · Cloud / SaaS

Applicability

Horizon-scanning material for computerized systems and AI in applicable GMP manufacturing contexts.

What Changed

The drafts proposed updated lifecycle, supplier, data-integrity, security, AI model, performance, monitoring, and human-review expectations.

What Did Not Change

Consultation text is not final binding or operative guidance. Existing applicable requirements continue until formally replaced.

Practical Impact

Use the drafts to identify potential readiness questions without representing them as current law.

Actions to Consider

Map potentially affected controls and monitor official adoption. Label any resulting action as readiness work or professional interpretation.

Primary Source

Open the issuing-authority source

Revision history

Version 1.2 · 12 September 2026: Terminology and source fields standardized for Version 32.