U.S. Electronic Code of Federal Regulations

21 CFR Part 11 — Electronic Records; Electronic Signatures

Electronic records and electronic signatures within the scope defined by Part 11 and the applicable predicate rules.

Authority
U.S. Electronic Code of Federal Regulations
Source
21 CFR Part 11 — Electronic Records; Electronic Signatures
Type
Binding regulation
Status
Current regulation
Publication date
Current eCFR
Effective date
In force
Last reviewed
12 September 2026
Topics
Part 11 · Data Integrity

Applicability

Electronic records and electronic signatures within the scope defined by Part 11 and the applicable predicate rules.

What Changed

This record links to the current official text; it does not claim a new amendment.

What Did Not Change

Applicability remains record- and use-specific. The predicate rule, electronic reliance, and signature use must be understood.

Practical Impact

Maintain decisions for record integrity, access, audit trails, signatures, retention, accurate copies, and operational controls.

Actions to Consider

Identify the required record first, then assess the configured electronic workflow and applicable controls.

Primary Source

Open the issuing-authority source

Revision history

Version 1.2 · 12 September 2026: Terminology and source fields standardized for Version 32.